Clinical Trials

HUD authorized by Federal Law for use with neurovascular embolic coils in patients >18 years of age for the treatment of unruptured wide-necked intracranial aneurysms with neck widths of > 4mm or dome to neck ratio < 2 originating on or near a vessel bifurcation of the basilar tip or carotid terminus, with at least a portion of the aneurysm neck overlapping the lumen of the parent artery.

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

zzzMarshfield Medical Center

611 Saint Joseph Ave

Marshfield, WI 54449

The purpose of the Clinical Registry Investigating Bardet-Biedl Syndrome (CRIBBS) is to establish and perpetuate an international registry enabling subject recruitment for clinical natural history studies, therapeutic trials and collection of biological specimens of blood and saliva specimens of affected individuals and family members with a rare disorder, Bardet-Biedl syndrom (BBS). Biological specimens will be collected for future clinical studies, as well as other studies to examine the relationship between genetic mutations and clinical features. Specimens will be stored in the Core Laboratory.

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

Health Outcomes of Living Kidney Donation in Individuals Carrying a heterozygous Recessive Gene Mutation for Bardet-Biedl Syndrome: A Pilot Study. Sub-study of CRIBBS.

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

The purpose of this study is to perform further clinical, dental, biochemical, family, genetic and imaging evaluation of adults with persistent hypophosphatasemia who also harbor pathogenic, likely pathogenic or ALPL variants of uncertain significance and/or have elevated ALP substrates to more fully characterize this cohort and to determine what proportion may have previously unrecognized adult HPP.

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

The primary objective is to compare high-dose trivalent influenza to standard-dose quadrivalent vaccine on time to first occurrence of death or cardiopulmonary hospitalization within within each enrolling season.

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

The purpose of this study is to measure how effective and how safe zolmitriptan nasal spray is for acute migraine headaches in children ages 6-11 years old and is and is an investigational drug in participants in this age range.

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (S1400). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will be assigned to compare new targeted cancer therapy, designed to block the growth and spread of cancer, or combinations to standard of care therapy with the ultimate goal of being able to approve new targeted therapies in this setting. In addition, the protocol includes a non-match sub-study which will include all screened patients not eligible for any of the biomarker-driven sub-studies. This sub-study will compare a non-match therapy to standard of care also with the goal of approval.

MC - Chippewa Falls Center

2655 CTY HWY I

CHIPPEWA FALLS, WI 54729

MC - Wausau Center

2727 PLAZA DRIVE

WAUSAU, WI 54401

MC - Wisconsin Rapids Center

220 24TH ST SOUTH

WISCONSIN RAPIDS, WI 54494

MMC - Eau Claire

2310 Craig Rd

Eau Claire, WI 54701

MMC - Ladysmith

906 College Ave W

Ladysmith, WI 54848

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

MMC - Minocqua

9576 Highway 70

MINOCQUA, WI 54548

MMC - Rice Lake

1700 W STOUT ST

RICE LAKE, WI 54868

MMC - River Region at Stevens Point

4100 State Highway 66

Stevens Point, WI 54482

MMC - Weston

3400 Ministry Parkway

WESTON, WI 54476

The main purpose of this study is to find out if the MenACYW conjugate vaccine is safe when given at the same time with the childhood vaccines recommended in the US. MenACYW conjugate vaccine will be compared to a US-licensed meningococcal vaccine called Menveo. The licensed vaccine protects against meningococcal disease caused by 4 types of germs (A, C, Y and W)

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

This subprotocol (EAY131-Z1E) should be used in conjunction with the MATCH Master Protocol (EAY131).

MC - Wausau Center

2727 PLAZA DRIVE

WAUSAU, WI 54401

MMC - Eau Claire Cancer Center

2200 Craig Road

Eau Claire, WI 54701

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

MMC - Minocqua

9576 Highway 70

MINOCQUA, WI 54548

MMC - Rice Lake

1700 W STOUT ST

RICE LAKE, WI 54868

MMC - River Region at Stevens Point

4100 State Highway 66

Stevens Point, WI 54482

MMC - Weston

3400 Ministry Parkway

WESTON, WI 54476

This randomized phase II/III trial studies how well whole-brain radiation therapy works and compares it with or without hippocampal avoidance in treating patients with small cell lung cancer that is found in one lung, the tissues between the lungs, and nearby lymph nodes only (limited stage) or has spread outside of the lung in which it began or to other parts of the body (extensive stage). Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. The hippocampus is part of the brain that is important for memory. Avoiding the hippocampus during whole-brain radiation could decrease the chance of side effects on memory and thinking. It is not yet known whether giving whole-brain radiation therapy is more effective with or without hippocampal avoidance in treating patients with small cell lung cancer.

MMC - Eau Claire

2310 Craig Rd

Eau Claire, WI 54701

MMC - Marshfield

1000 N OAK AVE

MARSHFIELD, WI 54449

MMC - River Region at Stevens Point

4100 State Highway 66

Stevens Point, WI 54482

zzzDiagnostic & Treatment Center

3401 CRANBERRY BLVD

WESTON, WI 54476